Platelet-activating factor and related lipid mediators

Cover of: Platelet-activating factor and related lipid mediators |

Published by Plenum Press in New York .

Written in English

Read online

Subjects:

  • Platelet activating factor.,
  • Platelet Activating Factor -- metabolism.

Edition Notes

Includes bibliographies and index.

Book details

Statementedited by Fred Snyder.
ContributionsSnyder, Fred.
Classifications
LC ClassificationsQP752.P62 P57 1987
The Physical Object
Paginationxix, 471 p. :
Number of Pages471
ID Numbers
Open LibraryOL2385292M
ISBN 100306425165
LC Control Number87014198

Download Platelet-activating factor and related lipid mediators

This volume records the proceedings of the Fifth International Con­ gress on PAF and Related Lipid Mediators, held at the Free University Medical Hospital Ben­ jamin Franklin in Berlin, from SeptemberWe are very much indebted to Free Uni­ versity Berlin for providing tremendous facilities and financial support.

Platelet-activating factor (PAF) is the commonly used name for a group of potent biologically active, ether-linked phospholipids, the alkylacetylglycerophospho­ cholines. Following the identification of the chemical structure of P AF inmuch progress has been made in our understanding of.

Platelet-activating factor (PAF) is the commonly used name for a group of potent biologically active, ether-linked phospholipids, the alkylacetylglycerophospho­ cholines. Following the identification of the chemical structure of P AF inmuch progress has been made in our understanding of these phospholipid medi­ ators.

Platelet-Activating Factor and Related Lipid Mediators 2 Roles in Health and Disease. Editors: Nigam, Santosh, Kunkel, Gert, Prescott, Stephen M. (Eds.) Free Preview. The cellular sources of platelet-activating factor and related lipids; the biological properties of platelet-activating factor; and the effects of platelet-activating factor receptor antagonists are also considered.

Immunopharmacologists, immunologists, and pharmacologists will find the book invaluable. Additional Physical Format: Online version: Platelet-activating factor and related lipid mediators.

New York: Plenum Press, © (OCoLC) Platelet-activating factor is a very potent and short-lived lipid messenger Platelet-activating factor (PAF) is known to have a wide range of actions, operating as a mediator of inflammatory and immune responses, a second messenger, and a potent inducer of gene expression in neural systems (Fig.

).Cited by: 3. Purchase Lipid Mediators - 1st Edition. Print Book & E-Book. ISBNBook Edition: 1. Get this from a library. Platelet-activating factor and related lipid mediators 2: roles in health and disease. [S K Nigam; Gert Kunkel; Stephen M Prescott;] -- Comprises the proceedings of the Fifth International Congress held in Berlin in September, The volume's 62 contributions distill the current state of knowledge on the chemistry, biology.

Platelet-Activating Factor and Related Lipid Mediators 2: Roles in Health and Disease / Edition 1. by Santosh Nigam, This volume records the proceedings of the Fifth International Con­ gress on PAF and Related Lipid Mediators, held at the Free University Medical Hospital Ben­ jamin Franklin in Berlin, from SeptemberPrice: $ Find many great new & used options and get the best deals for Advances in Experimental Medicine and Biology: Platelet-Activating Factor and Related Lipid Mediators 2 No.

2: Roles in Health and Disease (, Hardcover) at the best online prices at eBay. Free shipping for many products. Platelet-activating factor Article Literature Review (PDF Available) in Journal of Biological Chemistry (29) November with 2, Reads How we measure 'reads'. Purchase Arachidonate Related Lipid Mediators, Volume - 1st Edition.

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Free 2-day shipping. Buy Advances in Experimental Medicine and Biology: Platelet-Activating Factor and Related Lipid Mediators 2: Roles in Health and Disease (Hardcover) at   This chapter reviews lipid mediators which include prostaglandins (PGs), leukotrienes (LTs), endocannabinoids, platelet‐activating factor (PAF), lysophosphatidic acid (LPA), sphingosine‐1‐phosphate (S1P), and others.

PGs are involved in elicitation of Author: Shuh Narumiya, Takehiko Yokomizo, Junken Aoki. Platelet-activating factor (PAF) production by human embryos is related to pregnancy potential.

METHODS: Conditioned embryo culture media were obtained following conventional IVF on day 3, with PAF levels and pregnancy outcomes by: Lipid Mediators in the Immunology of Shock (Nato Science Series A:): Medicine & Health Science Books @ At the â Fifth International Congress on PAF and Related Lipids â in Berlin in Septembera team from Japan reported that a competitive antagonist of the a The â Fifth International Congress on Platelet-activating Factor and Related Lipid Mediators â was held in Berlin, 12â 16 September, Embryonic platelet-activating factor: an indicator of J.E.

() Embryonic platelet activating factor production in the rabbit. Factor and Related Lipid Mediators, New Orleans, LA. Platelet-activating factor (PAF) is a lipid mediator involved in several allergic reactions.

It is released from multiple cells of the immune system, such as eosinophils, neutrophils, and mast cells, and also exerts its effect on most of them upon specific binding to its receptor, becoming a pleiotropic mediator. PAF is considered a potential relevant mediator in allergic rhinitis, with a key Cited by: 1.

The Role of Platelet-Activating Factor in Immune Disorders: Meeting of the 'Fondation IPSEN pour la Recherche Thérapeutique', Paris, JunePart in Lipid Mediators Research, Vol.

2) (v. 2) [P. Braquet] on *FREE* shipping on qualifying offers. The platelet-activating factor receptor is a G-protein coupled receptor which binds platelet-activating factor. The PAF receptor shows structural characteristics of the rhodopsin (MIM ) gene family and binds platelet-activating factor (PAF).

PAF is a phospholipid (alkylacetyl-sn-glycerophosphorylcholine) that has been implicated as a mediator in diverse pathologic processes Aliases: PTAFR, PAFR, platelet activating factor receptor.

Language: English ISBN:LCCN: MeSH: Platelet Activating Factor/chemistryPlatelet Activating Factor/physiology* Publication Type(s): Congresses Notes: "Proceedings of the Fifth International Congress on Platelet-Activating Factor and Related Lipid Mediators, held September, in Berlin, Germany"--T.p.

Arachidonic Acid and Docosahexaenoic Acid-derived Lipid Mediators in Brain - Pp. (9) Akhlaq A. Farooqui. PDF The Roles of Platelet-Activating Factor (PAF) and its Related Signaling and Metabolism in Neurological Diseases Directions for Future Development on Various Aspects of Neurodegeneration and Neuroprotection in Neurological Cited by: 4.

Author(s): Snyder,Fred Title(s): Platelet-activating factor and related lipid mediators/ edited by Fred Snyder. Country of Publication: United States Publisher: New York: Plenum Press, c   Comprising 29 chapters divided into four major parts, the book describes the molecular natures of enzymes, transporters, and receptors for lipid mediators (Part I), the function of lipid mediators in Drosophila and Zebrafish (Part II), the relationships between lipid mediators and various diseases (Part III), and detailed procedures of Brand: Springer Japan.

The biology of arachidonic acid, platelet-activating factor, and lysophosphatidic acid and the role they play in airway inflammation; Products of arachidonic acid metabolism such as leukotrienes, prostaglandins, epieicosatrienoic acid, and oxoeicosatetraenoic acid; Proresolution lipid mediators in inflammatory airway disease conditions.

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Platelet-Activating Factor and Related Lipid Mediators 2. Santosh K. Nigam. 01 Jul Paperback. US$ Platelet-Activating Factor and Related Lipid Mediators 2.

Santosh Nigam. 15 Jan Paperback. Other glycerophospholipid-derived lipid mediators are platelet-activating factor, lysophosphatidic acid, and endocannabinoids.

Degradation of sphingolipids also results in the generation of sphingolipid-derived lipid mediators. Sphingolipid-derived lipid mediators are ceramide, ceramide 1-phosphate, sphingosine, and sphingosine by: Several protein growth factors can induce endothelial cell proliferation and angiogenesis, through signal transduction cascades that result in the production of several inflammatory mediators and lipid second messengers such as prostaglandins and Platelet Activating Factor (PAF).Cited by: Title: Food Ingredients and Lipid Mediators VOLUME: 3 ISSUE: 4 Author(s):Tzortzis Nomikos, Elizabeth Fragopoulou and Smaragdi Antonopoulou Affiliation lou Street,Athens, Greece.

Keywords:lipid mediators, platelet activating factor, food ingredients, nutrition, inflammation, thrombosis Abstract: Lipid mediators are a heterogenous group of bioactive lipids which includes Cited by: Barletta et al., "Synthesis of platelet-activating factor (PAF) in transformed cell lines of a different origin," Prostaglandins & Other Lipid Mediators, vol.

Modulation of Tumor-Associated Macrophages (TAM) Phenotype by Platelet-Activating Factor (PAF) Receptor. Among these mediators is sphingosine 1-phosphate (S1P), a lipid growth factor that promotes endothelial integrity and which may be a therapeutic agent in capillary leak syndromes.[71, 72] Thus, platelets – by direct thrombotic action and through release of specific mediators – can provide protection of respiratory function by decreasing the Author: Brian P.

O’Sullivan, Steven W. Kerrigan. Lipid-derived autacoids play important roles in the inflammatory response and are a major focus of research into new anti-inflammatory drugs. These compounds include the eicosanoids such as prostaglandins, prostacyclin, leukotrienes, and thromboxane A and the modified phospholipids such as platelet activating factor (PAF).

This book summarizes the most recent progress in the studies of lipid mediators from the molecular to clinical level and introduces newly created tools for analysis including imaging mass spectrometry.

Comprising 29 chapters divided into four major parts, the book describes the molecular natures of enzymes, transporters, and receptors for lipid mediators (Part I), the function of lipid. – What constitutes a lipid and how it is broken down to generate biologically active mediators – The role of enzymes in the process of lipid mediator synthesis – The biology of arachidonic acid, platelet-activating factor, and lysophosphatidic acid and the role they play in airway inflammation.

Chair, 8th International Congress on “Platelet-Activating Factor and Related Lipid Mediators,” New Orleans, LA Chair, Organizer and President, Thirtieth Annual American Society for Neurochemistry Meeting, New Orleans, LA Organizer and Chair, Fourth International Workshop on Maturation Phenomenon in and.

This review will collate the bioactive lipid research to date and summarize the major pathways involved in their biosynthesis and role in inflammation. Specifically, lipids derived from AA (prostanoids, leukotrienes, 5-oxo-6,8,11,eicosatetraenoic acid, lipoxins, and epoxyeicosatrienoic acids), EPA (E-series resolvins), and DHA (D-series Cited by: Chair, 8th International Congress on “Platelet-Activating Factor and Related Lipid Mediators,” New Orleans, LA Chair, Organizer and President, Thirtieth Annual American Society for Neurochemistry Meeting, New Orleans, LA Organizer and Chair, Fourth.

The structural identification of platelet-activating factor (PAF) in was an exciting milestone in lipid science for those of us who were around then, as it was the first time that an intact phospholipid was found to have biological activity in its own right, and not simply to have a structural function in membranes, or to act via.Platelets are a kind of blood cells derived from bone marrow megakaryocytes and play essential roles in thrombosis, hemostasis, and tissue repair.

Platelets have been found to be crucially involved in various immune responses and actively involved in the pathogenesis of allergic diseases such as allergic asthma. Patients with allergic asthma have lower platelet counts and increased levels of Author: Mirjana Turkalj, Ivana Banic.

Abstract. Alzheimer’s disease (AD) is associated with oxidative damage of low density lipoproteins (ox-LDL). In order to investigate whether higher levels of ox-LDL are related to alterations of the activity of enzymes involved in lipid metabolism, we studied the activity of paraoxonase-1 (PON1) and platelet activating factor acetylhydrolase (PAF-AH) in AD patients and the relationship Cited by:

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